WASHINGTON (AP) — A federal deal worker stole an FBI agent’s auto from your bureau’s headquarters in Washington and attempted to get into a restricted facility in advance of he was arrested, authorities explained in court docket documents filed Wednesday.
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This might enable reveal why older Females are more likely to bear kids with chromosomal Diseases like Down Syndrome, in which an extra copy of chromosome 21 finds its way into an oocyte — and later on, an embryo.
Munakata and Namekawa will Assess mice with typical and mutated versions with the chromatin remodeler. Since the mice develop and experienced, they're going to observe whether or not the presence or absence of the protein triggers variations from the arrangement of DNA spools during the animals’ oocytes. And they're going to watch whether or not this, in turn, alters the pattern of gene expression over time.
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Namekawa believes that in human oocytes, variations in these designs could disrupt the fragile choreography of genes staying turned on and off at the correct situations — leaving them unprepared for fertilization or progress into wholesome embryos. Adjustments in chromatin composition as an oocyte ages may also effect just how that chromosomes segregate for the duration of cell division.
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